The APAYAO STATE COLLEGE grew from the establishment of the Conner Vocational High School (CVHS) at Ripang, Conner, Apayao on July 1, 1971, to the transfer in 1974 to its permanent 4.8-hectare site in Malama donated by the late Albert Bengan and Sabas Gorospe. Two-year technical courses were then introduced in 1976 to meet the occupation requirements of the community. The purchase of an adjacent 2.97-hectare lot in 1982 contributed to the expansion of the campus.
CVHS was later converted to into the Kalinga-Apayao School of Arts and Trades (KASAT) in 1978. KASAT already began to offer Bachelor of Secondary Education in addition to its existing secondary and non-degree programs. To meet the education needs of neighbouring municipalities and nearby communities, an extension campus of KASAT was established in San Isidro, Luna, Apayao, housed in the then private secondary school Luna Academy which was acquired through Congressional Development Fund.
Under the supervision of the Commission on Higher Education (CHED), KASAT progressed into the Apayao Institute of Science and Technology (AIST) by R.A. 7856 in 1994 to respond to the growing demand for science and technology programs. Being the only Higher Education Institution (HEI) in the province, AIST expanded its curricular program offerings to include Bachelor of Science in Computer Science and Bachelor of Science in Architecture, and Bachelor of Science in Forestry.
AIST advanced into a chartered institution as the APAYAO STATE COLLEGE in February 26, 1998 through Republic Act 8563 following the separation of Apayao from Kalinga to be a distinct province in 1995.
Offering ten degree curricular programs and the Laboratory secondary education at the Main Campus in Malama, Conner and also ten degree curricular programs in the Extension Campus in Luna, Apayao, including the different short technical courses, the Apayao State College remains to be the only institution of higher learning in the entire province. The college continues to grow through the projected offering of a wider range of degree programs, the culture of research, and its involvement in community improvement through the college extension and development programs.